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Home > Wen Yuan (Middle School Edition) > 2021 No.05 > 氨基糖苷类抗生素的杂质谱研究

  • 氨基糖苷类抗生素的杂质谱研究

    Author(s)：

    刘雅萱；张文志

    Publication Title：

    Wen Yuan (Middle School Edition) 2021 No.05

    Affiliations：

    通化市食品药品检验所 吉林 通化 134000

    Abstract：

    氨基糖昔类抗生素是通过微生物发酵合成的药物,发酵副产物较多,结构组成复杂,异构体降解副产物较多,极易影响药品质量.通过合理地确定特定杂质和杂质限度以及杂质来源,不仅能提高药品的质量控制水平,还能指导生产工艺的优化并提高药品的质量.因此对氨基糖昔类抗生素进行杂质谱研究是药品质量控制和研发生产的重要环节,对提高药品的整体质量具有十分重要的意义.

    Keywords：

    氨基糖苷类抗生素;杂质谱研究;方法

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    [1] 刘雅萱；张文志.氨基糖苷类抗生素的杂质谱研究[J].Wen Yuan (Middle School Edition),2021(05),.

文渊(中学版)
Wen Yuan (Middle School Edition)

Language: 中文

CN：11-9275/G

ISSN：2096-627X

Publication Frequency: 月刊

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